BDP2-package: Bayesian Adaptive Designs for Phase II Trials with Binary...

In wiesenfa/BDP2: Bayesian Adaptive Designs for Phase II Trials with Binary Endpoint

Description

Tools and workflow to choose design parameters in Bayesian adaptive single-arm phase II trial designs with binary endpoint (response, success) with possible stopping for efficacy and futility at interim analyses. Also contains routines to determine and visualize operating characteristics. See Kopp-Schneider et al. (2018) <doi:10.1002/bimj.201700209>.

Details

The DESCRIPTION file: This package was not yet installed at build time.
Index: This package was not yet installed at build time.
Tools and workflow to choose design parameters in Bayesian adaptive single-arm phase II trial designs with binary endpoint (response, success) with possible stopping for efficacy and futility at interim analyses. Also contains routines to determine and visualize operating characteristics.

Main functions: BDP2workflow, BDP2 and plotBDP2. BDP2workflow provides an interactive shiny app which also generates Word/pdf/html reports.

Author(s)

Annette Kopp-Schneider, Manuel Wiesenfarth, Ulrich Abel

Maintainer: Manuel Wiesenfarth <[e-mail]>

References

Kopp-Schneider, A., Wiesenfarth, M., Witt, R., Edelmann, D., Witt, O. and Abel, U. (2018).
Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions - a calibration approach. Biometrical Journal, to appear.

Examples

## Not run: 
# Starts Shiny app
  BDP2workflow()

## End(Not run)

wiesenfa/BDP2 documentation built on April 11, 2021, 8:06 p.m.