variation.within.cell.line: Variation within cell line

In yavorska/AchillesPackage: Achilles Application Functions

Description

Generate a plot comparing the LFC values of each shRNA of a given gene within a chosen cell line.

Usage

variation.within.cell.line(object, cancerID, geneName, type = "all", ...)

Arguments

object	An RNAi object.
cancerID	a character string indicating the cell line of interest (partial string matching is sufficient).
geneName	A character string giving the name of the gene in question, e.g. "MDM4".
type	The style of plot one wishes to show, can be one of "all" or "median".
...	Any other additions to the ggplot. One can change the theme, plot name, etc. as desired.

Value

A ggplot object.

Examples

data("Achilles2.4_Data")
data("Achilles2.4_annotation")

RNAiObject <- new(Class = "RNAi", genes = Achilles2.4_Data$Gene,
                  sequences = Achilles2.4_Data$Name,
                  cancers = colnames(Achilles2.4_Data)[-(1:2)],
                  cancersP53 = Achilles2.4_annotation,
                  values = Achilles2.4_Data[,-(1:2)])

variation.within.cell.line(object = RNAiObject, cancerID = "SLR24", geneName = "MDM4", type = "all")

yavorska/AchillesPackage documentation built on May 4, 2019, 2:31 p.m.