Description Usage Arguments Value Author(s) References
Implement the Smith-Waterman Algorithm to produce local pairwise sequence alignment
1 | SWalgorithm(seq1, seq2, subMatrix, gapOpening = 8, gapExtension = 8)
|
seq1 |
input the first sequence |
seq2 |
input the second sequence |
subMatrix |
substitution matrix for protein sequence alignment or score matrix for DNA/RNA sequence alignment |
gapOpening |
the penalty for opening a gap in the alignment |
gapExtension |
the penalty for extending a gap by one residue |
path |
the optimal path in pairwaise sequence alignment |
fMatrix |
the score table used in pairwise sequence alignment to determine optimal path |
bestScore |
the best score(s) in local pairwise sequence alignemtn to start the track back |
Yu Gu
Durbin, Richard, Sean R. Eddy, Anders Krogh, and Graeme Mitchison. Biological sequence analysis: probabilistic models of proteins and nucleic acids. Cambridge university press, 1998.
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