GeneExpressionSignature_package: Introduction to the GeneExpressionSignature Package
In zhilongjia/GeneExpressionSignature: Gene Expression Signature based Similarity Metric
Description
The GeneExpressionSignature add-on is an implementation of computing
distances among preprocessed gene-expression profiles of samples for . The
distances can be used to detect similarities among the signatures of drugs,
diseases, and biological states of interest, and construct connectivity map.
Details
This package contains functions for the distances computation based on gene
expression signature. First, list of genes is ranked according to their
expression ratios to produce the Prototype Ranked List (PRL). Second, all
the PRLs with the same state are aggregated by RankMerging
functions. Finally, all the ranked lists are made as one input of the
ScorePGSEA and ScoreGSEA functions to compute
the pairwise distances.
zhilongjia/GeneExpressionSignature documentation built on May 4, 2019, 11:21 p.m.
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Description
The GeneExpressionSignature add-on is an implementation of computing distances among preprocessed gene-expression profiles of samples for . The distances can be used to detect similarities among the signatures of drugs, diseases, and biological states of interest, and construct connectivity map.
Details
This package contains functions for the distances computation based on gene
expression signature. First, list of genes is ranked according to their
expression ratios to produce the Prototype Ranked List (PRL). Second, all
the PRLs with the same state are aggregated by RankMerging
functions. Finally, all the ranked lists are made as one input of the
ScorePGSEA and ScoreGSEA functions to compute
the pairwise distances.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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