This function fits hierarchical generalized linear models (HGLMs) using various approximation methods.

1 2 3 4 5 6 7 8 9 10 | ```
HGLM(y = NULL, X = NULL, Z = NULL, X.disp = NULL,
family = gaussian(link = identity),
random.family = gaussian(link = identity), method = "EQL",
conv = 1e-04, maxit = 20, fixed = NULL, random = NULL,
disp = NULL, link.disp = "log", disp.random = NULL,
data = NULL, data.random = NULL, fix.disp = NULL,
Offset = NULL, Weights = NULL, disp.start = 0, binomial.N = NULL,
start.fixed = NULL, start.random = NULL, start.disp = NULL,
start.disp.random = NULL, info = TRUE, debug = FALSE,
contrasts = NULL)
``` |

`y` |
the dependent variable, only available when |

`X` |
a design matrix for the fixed effects, only available when |

`Z` |
an design matrix for the random effects, only available when |

`X.disp` |
a design matrix for the fixed effects in the dispersion part of the model, only available when |

`family` |
a description of the error distribution and link function to be used in the mean part of the model. (See |

`random.family` |
a description of the error distribution and link function to be used in the variance part of the model. |

`method` |
estimation method, which can be |

`conv` |
convergence criterion, the default is 1e-4, for models with many random effects could be set less strict. |

`maxit` |
maximum number of iterations in the IWLS algorithm, only available when |

`fixed` |
a |

`random` |
a one-sided |

`disp` |
a one-sided |

`link.disp` |
the link function for the dispersion part of the model, only available when |

`disp.random` |
a list of one-sided |

`data` |
the data frame to be used together with |

`data.random` |
a list of |

`Weights` |
prior weights to be specified in weighted regression, only available when |

`fix.disp` |
a numeric value if the dispersion parameter of the mean model is known for example 1 for binomial and Poisson models. |

`Offset` |
an offset for the linear predictor of the mean model. |

`disp.start` |
(starting) values for the overdispersion structure - vector of length equal to the number of parameters in the overdispersion structure, only available when |

`binomial.N` |
the number of trials for each observation for binomial models. |

`start.fixed` |
optional starting values for fixed effects in the mean structure (one vector of numeric values). |

`start.random` |
optional starting values for random effects in the mean structure (one vector of numeric values). |

`start.disp` |
optional starting values for parameters of dispersion components of the residuals (one vector of numeric values). |

`start.disp.random` |
optional starting values for parameters of dispersion components of random effects (one vector of numeric values). |

`info` |
a request to display of iteration information if |

`debug` |
a request to display of iteration mechanism progress in detail if |

`contrasts` |
see |

When `method = 'EQL'`

, all the model checking functions in the `hglm-package`

are available on the object returned; Otherwise, all the model checking functions in the `HGLMMM-package`

are available on the object returned.

When `method = 'EQL'`

, an object of class `hglm`

is returned, see `hglm`

; Otherwise, an object of class `HGLM`

is returned, see `HGLMfit`

.

The function provides a unified interface to the `hglm-package`

developed by Moudud Alam, Lars Ronnegard and Xia Shen, and the `HGLMMM-package`

developed by Marek Molas.

Xia Shen and Marek Molas

Lee, Y. and Nelder, J.A. (1996). Hierarchical generalized linear models (with discussion). *Journal of the Royal Statistical Society. Series B (Methological)*
**58**, 619-678.

Lee, Y. and Nelder, J.A. (2001). Hierarchical generalised linear models: A synthesis of generalised linear models, random-effect models and structured dispersions.
*Biometrika* **88**, 987-1006.

Lee, Y., Nelder, J.A., and Pawitan, Y. (2006). *Generalized Linear Models with Random Effects*. Boca Raton: Chapman & Hall/CRC.

Noh, M. and Lee, Y. (2007). REML estimation for binary data in GLMMs. *Journal of Multivariate Analysis* **98**, 896-915.

Ronnegard, L., Shen, X. and Alam, M. (2010). hglm: A Package for Fitting Hierarchical Generalized Linear Models. *The R Journal. (to appear)*

Molas, M. and Lesaffre, E. (2010). Hierarchical Generalized Linear Models: the R Package HGLMMM. **Submitted**.

`hglm-package`

, `HGLMMM-package`

, `hglm`

, `HGLMfit`

.

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 | ```
data(semiconductor)
# ----- use 'EQL'
h.gamma.normal <- HGLM(fixed = y ~ x1 + x3 + x5 + x6,
random = ~ 1|Device,
family = Gamma(link = log),
disp = ~ x2 + x3, data = semiconductor)
summary(h.gamma.normal)
plot(h.gamma.normal, cex = .6, pch = 1,
cex.axis = 1/.6, cex.lab = 1/.6,
cex.main = 1/.6, mar = c(3, 4.5, 0, 1.5))
# ----- use 'HL(0,1)'
RSC <- data.frame(int = rep(1, 16))
h.gamma.normal <- HGLM(fixed = y ~ x1 + x3 + x5 + x6,
random = ~ 1|Device,
family = Gamma(link = log),
disp = ~ x2 + x3, data = semiconductor,
method = 'HL01', disp.start = c(0, 0, 0),
disp.random = list(one = ~ 1), data.random = list(RSC))
# ----- use 'HL(1,1)'
RSC <- data.frame(int = rep(1, 16))
h.gamma.normal <- HGLM(fixed = y ~ x1 + x3 + x5 + x6,
random = ~ 1|Device,
family = Gamma(link = log),
disp = ~ x2 + x3, data = semiconductor,
method = 'HL11', disp.start = c(0, 0, 0),
disp.random = list(one = ~ 1), data.random = list(RSC))
``` |

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