DeMAND: DeMAND

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DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Author
Jung Hoon Woo <jw2853@columbia.edu>, Yishai Shimoni <ys2559@columbia.edu>
Date of publication
None
Maintainer
Jung Hoon Woo <jw2853@columbia.edu>, Mariano Alvarez <reef103@gmail.com>
License
file LICENSE
Version
1.4.0

View on Bioconductor

Man pages

bcellAnno
Annotation for the expression data
bcellExp
B cell expression data
bcellNetwork
B cell network
caseIndex
Case sample index
controlIndex
Control sample index
demandClass
The demand class constructor
demand-instance
The DeMAND instance
printDeMAND
Basic methods for class demand
runDeMAND
Run DeMAND algorithm

Files in this package

DeMAND/DESCRIPTION
DeMAND/LICENSE
DeMAND/NAMESPACE
DeMAND/R
DeMAND/R/KLD2D.r
DeMAND/R/demandClass.R
DeMAND/R/integratePvalues.r
DeMAND/R/pareto.R
DeMAND/R/printDeMAND.R
DeMAND/R/runDeMAND_ys.R
DeMAND/build
DeMAND/build/vignette.rds
DeMAND/data
DeMAND/data/inputExample.rda
DeMAND/inst
DeMAND/inst/doc
DeMAND/inst/doc/DeMAND.R
DeMAND/inst/doc/DeMAND.Rnw
DeMAND/inst/doc/DeMAND.pdf
DeMAND/man
DeMAND/man/bcellAnno.Rd
DeMAND/man/bcellExp.Rd
DeMAND/man/bcellNetwork.Rd
DeMAND/man/caseIndex.Rd
DeMAND/man/controlIndex.Rd
DeMAND/man/demand-instance.Rd
DeMAND/man/demandClass.Rd
DeMAND/man/printDeMAND.Rd
DeMAND/man/runDeMAND.Rd
DeMAND/vignettes
DeMAND/vignettes/DeMAND.Rnw