DeMAND: DeMAND

DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Getting started

Package details

AuthorJung Hoon Woo <jw2853@columbia.edu>, Yishai Shimoni <ys2559@columbia.edu>
Bioconductor views GeneExpression Network NetworkEnrichment StatisticalMethod SystemsBiology
MaintainerJung Hoon Woo <jw2853@columbia.edu>, Mariano Alvarez <reef103@gmail.com>
Licensefile LICENSE
Version1.20.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DeMAND")

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DeMAND documentation built on Nov. 8, 2020, 8:22 p.m.