DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.

Getting started

Package details

AuthorJung Hoon Woo <>, Yishai Shimoni <>
Bioconductor views GeneExpression Network NetworkEnrichment StatisticalMethod SystemsBiology
MaintainerJung Hoon Woo <>, Mariano Alvarez <>
Licensefile LICENSE
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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DeMAND documentation built on Nov. 8, 2020, 8:22 p.m.