Description Usage Arguments Details Value Author(s) Examples
Convert methylation beta value to M value.
1 | B2M(x)
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x |
An numeric matrix with values between 0 and 1 |
Methylation beta value is calculated as beta=M/(M+U+a). M is methylated intensity, U is unmethylated intensity, and a is a constant offset (by default , a=100). M value is calculated as M=log2((M+a)/(U+a)). M or U is usually greater than 1000, so a is negligible for most probes. if a=0, then M=log2(beta)/(1-beta).
A matrix of M values
Zongli Xu
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