EpiDISH: Epigenetic Dissection of Intra-Sample-Heterogeneity

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of whole blood, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

Package details

AuthorAndrew E. Teschendorff <a.teschendorff@ucl.ac.uk>, Shijie C. Zheng<shijieczheng@gmail.com>
Bioconductor views DNAMethylation DifferentialMethylation Epigenetics ImmunoOncology MethylationArray
MaintainerShijie Charles Zheng<shijieczheng@gmail.com>
URL https://github.com/sjczheng/EpiDISH
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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EpiDISH documentation built on Nov. 8, 2020, 6:52 p.m.