GOTHiC: Binomial test for Hi-C data analysis

This is a Hi-C analysis package using a cumulative binomial test to detect interactions between distal genomic loci that have significantly more reads than expected by chance in Hi-C experiments. It takes mapped paired NGS reads as input and gives back the list of significant interactions for a given bin size in the genome.

Getting started

Package details

AuthorBorbala Mifsud and Robert Sugar
Bioconductor views Epigenetics HiC ImmunoOncology Preprocessing Sequencing
MaintainerBorbala Mifsud <b.mifsud@qmul.ac.uk>
LicenseGPL-3
Version1.26.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GOTHiC")

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GOTHiC documentation built on Nov. 8, 2020, 8:25 p.m.