GenoGAM: GenoGAM: A package providing a framework to analyse ChIP-Seq...

Description Author(s) See Also

View source: R/GenoGAM-class.R

Description

This package allows statistical analysis of genome-wide data with smooth functions using generalized additive models based on the implementation from the R-package 'mgcv'. It provides methods for the statistical analysis of ChIP-Seq data including inference of protein occupancy, and pointwise and region-wise differential analysis. Estimation of dispersion and smoothing parameters is performed by cross-validation. Scaling of generalized additive model fitting to whole chromosomes is achieved by parallelization over overlapping genomic intervals.

Author(s)

Maintainer: Georg Stricker georg.stricker@in.tum.de

Authors:

See Also

Useful links:


GenoGAM documentation built on Nov. 8, 2020, 7:45 p.m.