Description Usage Arguments Details Value Examples
Fits a power-law relationship between mean expression and dispersion.
1 | NBumiFitDispVsMean(fit, suppress.plot=TRUE)
|
fit |
output from NBumiFitModel or NBumiFitBasicModel. |
suppress.plot |
Whether to plot the calculated fit. |
Fits a power-law relationship between mean expression and fitted gene-specific dispersions, using linear regression on ln transformed values. Lowly expressed genes, mean expression < 2^4, are excluded as long as at least 2000 genes remain for fitting.
Coefficients of linear regression.
1 2 3 4 5 | library(M3DExampleData)
counts <- as.matrix(Mmus_example_list$data);
counts <- counts[rowSums(counts) > 0,];
fit <- NBumiFitModel(counts);
coeffs <- NBumiFitDispVsMean(fit, suppress.plot=TRUE);
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