M3Drop: Michaelis-Menten Modelling of Dropouts in single-cell RNASeq

This package fits a Michaelis-Menten model to the pattern of dropouts in single-cell RNASeq data. This model is used as a null to identify significantly variable (i.e. differentially expressed) genes for use in downstream analysis, such as clustering cells.

Package details

AuthorTallulah Andrews <tallulandrews@gmail.com>
Bioconductor views DifferentialExpression DimensionReduction FeatureExtraction GeneExpression RNASeq Sequencing Software Transcriptomics
MaintainerTallulah Andrews <tallulandrews@gmail.com>
LicenseGPL (>=2)
URL https://github.com/tallulandrews/M3Drop
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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M3Drop documentation built on Nov. 8, 2020, 5:06 p.m.