OVESEG-package: OVESEG: A package for marker gene test.

Description References

Description

Function OVESEGtest performs OVESEG-test for expression profiles from multiple groups to detect subtype-specific marker genes. While it may take a long time to execute permutations for p-value estimation, users can apply OVESEGtstat to obtain OVESEG-test statistics to rank genes and apply postProbNull to obtain each gene's posterior probabilities of component null hypotheses. nullDistri estimates probabilities of any one group being upregulated under null hypotheses. patternDistri estimates probabilities of all kinds of upregulation patterns among groups.

References

Chen, L., Herrington, D., Clarke, R., Yu, G., and Wang, Y. (2019). <e2><80><9c>Data-Driven Robust Detection of Tissue/Cell-Specific Markers.<e2><80><9d> bioRxiv. https://doi.org/10.1101/517961.


OVESEG documentation built on Nov. 8, 2020, 4:51 p.m.