R/kristensen.R

In PrInCE: Predicting Interactomes from Co-Elution

#' Interactome of HeLa cells
#' 
#' Co-elution profiles derived from size exclusion chromatography (SEC) of
#' HeLa cell lysates.
#' 
#' Protein quantitation was accomplished by SILAC (stable isotopic labelling
#' by amino acids in cell culture), and is ratiometric, i.e., it reflects 
#' the ratio between the intensity of the heavy isotope and the light isotope 
#' ("H/L"). The dataset was initially described in Kristensen et al., 
#' \emph{Nat. Methods} 2012. The medium isotope channel from replicate
#' 1 (Supplementary Table 1a in the online supplementary information) is 
#' included in the \code{PrInCE} package. The R script used to generate
#' this matrix from the supplementary materials of the paper is provided in the
#' \code{data-raw} directory of the package source code.
#'
#' @docType data
#' @usage data(kristensen)
#' @format a data frame with 1875 rows and 48 columns, with proteins in rows and
#'   SEC fractions in columns
#' @source \url{https://www.nature.com/articles/nmeth.2131}
"kristensen"