compareHits: Searching for common hits between different scoring methods

In RNAither: Statistical analysis of high-throughput RNAi screens

Description

Searches for common hits between different scoring methods.

Usage

compareHits(hitVec1, hitVec2, namesHitVec1, namesHitVec2)

Arguments

hitVec1, hitVec2	the two binary hit vectors to be compared
namesHitVec1, namesHitVec2	the names of the siRNAs corresponding to the hit vectors

Value

Returns a character vector indicating which siRNAs are identified as hits in two different hit scoring schemes.

See Also

vennDiag , Ttest, MannWhitney

Examples

data(scoredDataset1, package="RNAither")
data(pValVec1, package="RNAither")

data(scoredDataset2, package="RNAither")
data(pValVec2, package="RNAither")

##for details on the generation of pValVec and scoredDataset,
##see the examples of the functions Ttest and MannWhitney linked above.

scoredHits1 <- hitselectionPval(scoredDataset1, pValVec1, "SigIntensity", "Hits1", 0.05, 
"GeneName", "pvalue_testfile1.txt")
scoredHits2 <- hitselectionPval(scoredDataset2, pValVec2, "SigIntensity", "Hits2", 0.05, 
"GeneName", "pvalue_testfile2.txt")

hitVector1 <- scoredHits1[[2]]
hitVector2 <- scoredHits2[[2]]

common_hits <- compareHits(hitVector1, hitVector2, names(hitVector1), names(hitVector2))

RNAither documentation built on Nov. 8, 2020, 8:06 p.m.