Ttest: Perform a Student's t-test

In RNAither: Statistical analysis of high-throughput RNAi screens

Description

Performs a Student's t-test on the intensity data.

Usage

Ttest(dataset, listofargs)

Arguments

dataset

an R data frame generated with generateDatasetFile

listofargs

a list containing: - "g" (greater) for significant increase, "l" (lower) for significant decrease, or "two.sided" for both - either a number indicating the true value of the mean, or a character string indicating the name of the gene to compare with - a character string specifying the column whose values will be used for the test - a character string specifying the name of the dataset column to be used to define the replicate, e.g. "GeneName" or "Internal_GeneID"

Value

Returns a list containing:

pValVec	a named vector of p-values
dataset	the dataset with an added column "p.value.mannwhitney"
paste("pValue.ttest", testType, sep="_")	the character string "pValue.ttest" concatenated with the testType (first element of listofargs)
"t test"	the character string "t test"

See Also

MannWhitney, RankProduct

Examples

data(exampleHeader, package="RNAither")
data(exampleDataset, package="RNAither")

pvals1 <- Ttest(dataset, list("l", median(dataset$SigIntensity, na.rm=TRUE), "SigIntensity", "GeneName"))
pValVec1 <- pvals1[[1]]
scoredDataset1 <- pvals1[[2]]

RNAither documentation built on Nov. 8, 2020, 8:06 p.m.