TFHAZ: Transcription Factor High Accumulation Zones
Version 1.0.0

It finds trascription factor (TF) high accumulation DNA zones, i.e., regions along the genome where there is a high presence of different transcription factors. Starting from a dataset containing the genomic positions of TF binding regions, for each base of the selected chromosome the accumulation of TFs is computed. Three different types of accumulation (TF, region and base accumulation) are available, together with the possibility of considering, in the single base accumulation computing, the TFs present not only in that single base, but also in its neighborhood, within a window of a given width. Then, high accumulation DNA zones are defined as regions of the genome formed by contiguous bases with accumulation equal or higher than a given threshold. In addition, some functions are provided in order to analyze, visualize and compare results obtained with different input parameters.

Package details

AuthorAlberto Marchesi, Marco Masseroli
Bioconductor views BiologicalQuestion ChIPSeq Coverage Software Transcription
MaintainerAlberto Marchesi <[email protected]>
Package repositoryView on Bioconductor
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TFHAZ documentation built on Nov. 17, 2017, 1:54 p.m.