calcLDSizeFactors: Compute normalizing factors for each sample

In diffloop: Identifying differential DNA loops from chromatin topology data

Description

calcLDSizeFactors takes a loops object computes size factors based for each sample

Usage

calcLDSizeFactors(dlo)

## S4 method for signature 'loops'
calcLDSizeFactors(dlo)

Arguments

dlo	A loops object with unnormalized size factors

Details

This function updates the loops object with new sizeFactor values for each sample in the colData slot using a method identical to that employed in DESeq2.

Value

A loops object with new size factors in colData

Examples

# Computing normalizing factors from the full ChIA-PET Data
rda<-paste(system.file('rda',package='diffloop'),'loops.small.rda',sep='/')
load(rda)
loops.small <- calcLDSizeFactors(loops.small)

diffloop documentation built on Nov. 8, 2020, 5:48 p.m.