gQTLstats-package: gQTLstats: computationally efficient analysis for eQTL and...

Description Details Author(s)

Description

computationally efficient analysis of eQTL, mQTL, dsQTL, etc.

Details

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This package addresses the management of map-reduce like computations for cis-association tests between DNA variants and genomic features like gene expression measurements. It makes essential use of data structures defined in package gQTLBase.

A number of experimental functions are present in the current version of the package: prep.cisAssocNB (assembles information to assess negative binomial regression in cis association testing), storeToMaxAssocBySNP (progress towards SNP-specific FDR), table_sensobj_thresh (reporting on sensitivity analysis).

Additional experimental functions are available to support scalable trans-gQTL testing TransChunk, filteredDFwPerm, and transTable operate on output of AllAssoc.

Author(s)

VJ Carey <stvjc@channing.harvard.edu>

Maintainer: VJ Carey <stvjc@channing.harvard.edu>


gQTLstats documentation built on Nov. 8, 2020, 7:53 p.m.