Description Usage Details Value Note Author(s) References See Also Examples
View source: R/triplex.table.R
The triplex.score.table
function returns default scoring tables
for parallel and antiparallel triplex types.
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This function is used by triplex.search
function to get
default scoring tables. These tables correspond exactly with Table 1 published
in (Lexa, 2011) and they represent the strength of Hoogsteen bonds between
thirdstrand nucleotide (row index) and a nucleotide from duplex (column index).
As a common triplet structure is H.WC:WC, to customize scoring tables
just use H as a row index, WC as a column index, then set desired score value and
pass such modified tables through score_table
option of triplex.search
interface.
Please keep in mind that for a mismatch (no bond at all) special value -9 is used.
If you want to change mismatch penalization, please use mis_pen
option of
triplex.search
function.
List of two matrixes, one for parallel triplex types and the other one for antiparallel.
If you modify the scoring tables,
you should consider changing also default P-value constants (lambda
,
mu
and rn
), because these are valid just for the default scoring tables.
Tomas Martinek, Jiri Hon
Lexa, M., Martinek, T., Burgetova, I., Kopecek, D., Brazdova, M.: A dynamic programming algorithm for identification of triplex-forming sequences, In: Bioinformatics, Vol. 27, No. 18, 2011, Oxford, GB, p. 2510-2517, ISSN 1367-4803
triplex.group.table
triplex.search
,
TriplexViews
,
triplex.diagram
,
triplex.3D
,
triplex.alignment
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