ASSISTant: Adaptive Subgroup Selection in Group Sequential Trials

Clinical trial design for subgroup selection in three-stage group sequential trial. Includes facilities for design, exploration and analysis of such trials. An implementation of the initial DEFUSE-3 trial is also provided as a vignette.

Author
Tze Leung Lai [ctb], Philip Lavori [aut], Olivia Liao [aut], Balasubramanian Narasimhan [aut, cre], Ka Wai Tsang [aut]
Date of publication
2016-05-03 01:35:52
Maintainer
Balasubramanian Narasimhan <naras@stat.Stanford.EDU>
License
GPL (>= 2)
Version
1.2-3
URLs

View on CRAN

Man pages

ASSISTant
Three stage group sequential adaptive design with subgroup...
ASSISTant-internal
Is a scalar quantity is a specified range?
ASSISTDesign
A class to encapsulate the adaptive clinical trial design of...
ASSISTDesignB
A fixed sample design to compare against the adaptive...
ASSISTDesignC
A fixed sample RCT design to compare against the adaptive...
DEFUSE3Design
The DEFUSE3 design
LLL.SETTINGS
Design and trial settings used in the Lai, Lavori, Liao paper...

Files in this package

ASSISTant
ASSISTant/inst
ASSISTant/inst/full_doc
ASSISTant/inst/full_doc/ASSISTant.Rmd
ASSISTant/inst/full_doc/ASSISTant.R
ASSISTant/inst/full_doc/defuse3.html
ASSISTant/inst/full_doc/ASSISTant.html
ASSISTant/inst/full_doc/defuse3.Rmd
ASSISTant/inst/full_doc/defuse3.R
ASSISTant/inst/doc
ASSISTant/inst/doc/ASSISTant.Rmd
ASSISTant/inst/doc/ASSISTant.R
ASSISTant/inst/doc/defuse3.html
ASSISTant/inst/doc/ASSISTant.html
ASSISTant/inst/doc/defuse3.Rmd
ASSISTant/inst/doc/defuse3.R
ASSISTant/NAMESPACE
ASSISTant/data
ASSISTant/data/LLL.SETTINGS.rda
ASSISTant/R
ASSISTant/R/LLL.SETTINGS.R
ASSISTant/R/ASSISTant.R
ASSISTant/R/ASSISTDesigns.R
ASSISTant/vignettes
ASSISTant/vignettes/ASSISTant.Rmd
ASSISTant/vignettes/defuse3.Rmd
ASSISTant/vignettes/assistant.bib
ASSISTant/README.md
ASSISTant/MD5
ASSISTant/build
ASSISTant/build/vignette.rds
ASSISTant/DESCRIPTION
ASSISTant/man
ASSISTant/man/LLL.SETTINGS.Rd
ASSISTant/man/ASSISTDesignB.Rd
ASSISTant/man/DEFUSE3Design.Rd
ASSISTant/man/ASSISTant-internal.Rd
ASSISTant/man/ASSISTant.Rd
ASSISTant/man/ASSISTDesignC.Rd
ASSISTant/man/ASSISTDesign.Rd