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`ASSISTant`

is a package to assist in performing **A**daptive **S**ubgroup **S**election **I**n **S**equential **T**rials.

`ASSISTant`

provides a three-stage adaptive group sequential clinical trial design with provision for selecting a subgroup where the treatment may be effective. The package provides facilities for design, exploration and analysis of such trials using either continuous or discrete outcomes. A complete implementation of the initial design for the DEFUSE-3 trial is also provided as a vignette.

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