computeMHPBoundaries: Compute the three modified Haybittle-Peto boundaries

In ASSISTant: Adaptive Subgroup Selection in Group Sequential Trials

Compute the three modified Haybittle-Peto boundaries

Description

Compute the three modified Haybittle-Peto boundaries

Usage

computeMHPBoundaries(prevalence, N, alpha, beta, eps, futilityOnly = FALSE)

Arguments

prevalence	the vector of prevalences between 0 and 1 summing to 1. J, the number of groups, is implicitly the length of this vector and should be at least 2.
N	a three-vector of total sample size at each stage
alpha	the type I error
beta	the type II error
eps	the fraction (between 0 and 1) of the type 1 error to spend in the interim stages 1 and 2
futilityOnly	a logical value indicating only the futility boundary is to be computed; default FALSE

Value

a named vector of three values containing btilde, b, c

ASSISTant documentation built on Dec. 2, 2022, 5:12 p.m.