GenGeno: Generate Genotypes

In AllelicSeries: Allelic Series Test

Generate Genotypes

Description

Generates genotypes in linkage equilibrium with accompanying annotations.

Usage

GenGeno(n, snps, maf_range = c(0.001, 0.005), prop_anno = c(0.5, 0.4, 0.1))

Arguments

n	Sample size.
snps	Number of SNP in the gene.
maf_range	Range of minor allele frequencies: c(MIN, MAX).
prop_anno	Proportions of annotations in each category. Length should equal the number of annotation categories. Default of c(0.5, 0.4, 0.1) is based on the approximate empirical frequencies of BMVs, DMVs, and PTVs.

Value

List containing the (n x snps) genotype matrix "geno" and the (snps x 1) annotation vector "anno".

AllelicSeries documentation built on April 3, 2025, 7:46 p.m.