SumCountSS: Allelic Sum Test from Sumstats

In AllelicSeries: Allelic Series Test

Allelic Sum Test from Sumstats

Description

Allelic Sum Test from Sumstats

Usage

SumCountSS(anno, beta, ld, se, weights, return_beta = FALSE)

Arguments

anno	(snps x 1) annotation vector with integer values in 1 through the number of annotation categories L.
beta	(snps x 1) vector of effect sizes for the coding genetic variants within a gene.
ld	(snps x snps) matrix of correlations among the genetic variants.
se	(snps x 1) vector of standard errors for the effect sizes.
weights	(L x 1) vector of annotation category weights. Note that the number of annotation categories L is inferred from the length of weights.
return_beta	Return estimated effect sizes and standard errors? Default: FALSE.

Value

If return_beta, a list containing the category effect sizes, standard errors, and the p-value. Otherwise, the numeric p-value only.

AllelicSeries documentation built on April 3, 2025, 7:46 p.m.