Prior transcription factor binding knowledge and target gene expression data are integrated in a Bayesian framework for functional cis-regulatory module inference. Using Gibbs sampling, we iteratively estimate transcription factor associations for each gene, regulation strength for each binding event and the hidden activity for each transcription factor.
|Author||Xi Chen [aut, cre], Jianhua Xuan [aut]|
|Maintainer||Xi Chen <[email protected]>|
|Package repository||View on CRAN|
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