X_sampling: Transcription Factor Activity Sampling Function

In BICORN: Integrative Inference of De Novo Cis-Regulatory Modules

Description

Function 'X_sampling' estimates the hidden activities of each transcription factor, according to a posterior Gaussian random process.

Usage

X_sampling(Y, C, A, X_old, base_line, C_prior, sigma_noise, sigma_A,
  sigma_baseline, sigma_X)

Arguments

Y	gene expression data matrix
C	sampled TF-gene binding network
A	sampled regulatory strength matrix
X_old	sampled transcription factor activity matrix from the previous round
base_line	sampled gene expression baseline activity
C_prior	prior TF-gene binding network
sigma_noise	variance of gene expression fitting residuals
sigma_A	variance of regulatory strength
sigma_baseline	variance of gene expression baseline activity
sigma_X	variance of transcription factor activity

BICORN documentation built on May 2, 2019, 2:05 a.m.