C_sampling_cluster: cis-Regulatory Module Sampling Function

In BICORN: Integrative Inference of De Novo Cis-Regulatory Modules

Description

Function 'C_sampling_cluster' samples a candidate cis-regulatory module for each gene, according to a discrete posterior probability distribution.

Usage

C_sampling_cluster(Y, C_old, A_old, X_old, base_line_old, C_prior, sigma_noise,
  sigma_A, sigma_baseline, sigma_X, BICORN_input)

Arguments

Y	gene expression data matrix
C_old	TF-gene binding network sampled from the previous round
A_old	regulatory strength matrix sampled from the previous round
X_old	transcription factor activity matrix sampled from the previous round
base_line_old	gene expression baseline activity sampled from the previous round
C_prior	prior TF-gene binding network
sigma_noise	variance of gene expression fitting residuals
sigma_A	variance of regulatory strength
sigma_baseline	variance of gene expression baseline activity
sigma_X	variance of transcription factor activity
BICORN_input	this list structure contains TF symbols, Gene symbols and candidate modules

BICORN documentation built on May 2, 2019, 2:05 a.m.