A_sampling: Regulation Strength Sampling Function

Description Usage Arguments

Description

Function 'A_sampling' estimates a regulation strength for each sampled binding event in C, according to a posterior Gaussian distribution.

Usage

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Arguments

Y

gene expression data matrix

C

sampled TF-gene binding network

A_old

regulatory strength sampled from the previous round, used as a prior in current function

X

sampled transcription factor activity matrix

base_line

sampled gene expression baseline activity

C_prior

prior TF-gene binding network

sigma_noise

variance of gene expression fitting residuals

sigma_A

variance of regulatory strength

sigma_baseline

variance of gene expression baseline activity

sigma_X

variance of transcription factor activity


BICORN documentation built on May 2, 2019, 2:05 a.m.