A_sampling: Regulation Strength Sampling Function

In BICORN: Integrative Inference of De Novo Cis-Regulatory Modules

Description

Function 'A_sampling' estimates a regulation strength for each sampled binding event in C, according to a posterior Gaussian distribution.

Usage

A_sampling(Y, C, A_old, X, base_line, C_prior, sigma_noise, sigma_A,
  sigma_baseline, sigma_X)

Arguments

Y	gene expression data matrix
C	sampled TF-gene binding network
A_old	regulatory strength sampled from the previous round, used as a prior in current function
X	sampled transcription factor activity matrix
base_line	sampled gene expression baseline activity
C_prior	prior TF-gene binding network
sigma_noise	variance of gene expression fitting residuals
sigma_A	variance of regulatory strength
sigma_baseline	variance of gene expression baseline activity
sigma_X	variance of transcription factor activity

BICORN documentation built on May 2, 2019, 2:05 a.m.