getCP: Estimate CP matrix from bootstraps

In BIGL: Biochemically Intuitive Generalized Loewe Model

Estimate CP matrix from bootstraps

Description

This function is generally called from within fitSurface.

Usage

getCP(bootStraps, null_model, transforms, sigma0, doseGrid)

Arguments

bootStraps	the bootstraps carried out already
null_model	Specified null model for the expected response surface. Currently, allowed options are "loewe" for generalized Loewe model, "hsa" for Highest Single Agent model, "bliss" for Bliss additivity, and "loewe2" for the alternative Loewe generalization.
transforms	Transformation functions. If non-null, transforms is a list containing 5 elements, namely biological and power transformations along with their inverse functions and compositeArgs which is a list with argument values shared across the 4 functions. See vignette for more information.
sigma0	standard deviation of the null model on the real data
doseGrid	a grid of dose combinations

Value

Estimated CP matrix

BIGL documentation built on Sept. 11, 2024, 6:12 p.m.