outsidePoints: List non-additive points

In BIGL: Biochemically Intuitive Generalized Loewe Model

List non-additive points

Description

List all points with corresponding p-values declared non-additive by the maxR statistical test.

Usage

outsidePoints(maxR, B = 10000)

Arguments

maxR	maxR statistics table returned by Ymean component from the output of maxR function. This can also be "maxR" element in the output of fitSurface function.
B	Iterations to use for the distribution of the maxR statistic. This is only used if Ymean dataframe does not have a "distr" attribute attached as is normally done when using fitSurface or maxR function.

Value

Returns a dataframe listing only dose combinations that exhibit significant deviations from the expected response surface.

Examples

  data <- subset(directAntivirals, experiment == 2)
  ## Data must contain d1, d2 and effect columns
  fitResult <- fitMarginals(data)
  surf <- fitSurface(data, fitResult, statistic = "maxR")
  outsidePoints(surf$maxR$Ymean)

BIGL documentation built on Sept. 11, 2024, 6:12 p.m.