CoreGx: Classes and Functions to Serve as the Basis for Other 'Gx' Packages

A collection of functions and classes which serve as the foundation for our lab's suite of R packages, such as 'PharmacoGx' and 'RadioGx'. This package was created to abstract shared functionality from other lab package releases to increase ease of maintainability and reduce code repetition in current and future 'Gx' suite programs. Major features include a 'CoreSet' class, from which 'RadioSet' and 'PharmaSet' are derived, along with get and set methods for each respective slot. Additional functions related to fitting and plotting dose response curves, quantifying statistical correlation and calculating area under the curve (AUC) or survival fraction (SF) are included. For more details please see the included documentation, as well as: Smirnov, P., Safikhani, Z., El-Hachem, N., Wang, D., She, A., Olsen, C., Freeman, M., Selby, H., Gendoo, D., Grossman, P., Beck, A., Aerts, H., Lupien, M., Goldenberg, A. (2015) <doi:10.1093/bioinformatics/btv723>. Manem, V., Labie, M., Smirnov, P., Kofia, V., Freeman, M., Koritzinksy, M., Abazeed, M., Haibe-Kains, B., Bratman, S. (2018) <doi:10.1101/449793>.

Getting started

Package details

AuthorPetr Smirnov [aut], Ian Smith [aut], Christopher Eeles [aut], Benjamin Haibe-Kains [aut, cre]
Bioconductor views Pharmacogenomics Software
MaintainerBenjamin Haibe-Kains <>
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:

Try the CoreGx package in your browser

Any scripts or data that you put into this service are public.

CoreGx documentation built on Dec. 20, 2019, 1:08 a.m.