mutantfreq: Cell mutant frequencies in children

In GLMsData: Generalized Linear Model Data Sets

Cell mutant frequencies in children

Description

The “somatic cell mutant frequencies at the hprt locus of the X-chromosome” in healthy children

Usage

data(mutantfreq)

Format

A data frame with 49 observations on the following 5 variables.

Donor

the donor identifier; a factor

Sex

the sex of the child; a factor with levels F (females) or M (males)

Age

the age of the child in completed years; a numeric vector

Ceff

the mean unselected cloning efficiency; a numeric vector

Mfreq

the mutant frequencies x 10e-06; a numeric vector

Details

In the original paper, the children are sometimes referred to as belonging to Group II (Ages 0 to 5), Group III (Ages 6 to 11) or Group IV (Ages 12 to 17). (Group I refers to cord data referenced to another article.) Age may be treated as categorical with these categories.

Source

B. A. Finette, L. M. Sullivan, J. P. O'Neill, J. A. Nicklas, P. M. Vacek and R. J. Albertini (1994) Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age. Mutation Research, 308, 223–231.

Examples

data(mutantfreq)
summary(mutantfreq)

GLMsData documentation built on Aug. 22, 2022, 9:10 a.m.