Description Usage Format Source References Examples
Data are from Thomson et al. (1986) and describe the counts of combinations of four different antigen classes in 45 French type I diabetes patients. HWE is equivalent to a recessive model, see Thomson (1983) and Wakefield (2009) for more details.
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A vector with 10 observations in the order n_{11},n_{11},n_{13},n_{14},n_{22},n_{23},n_{24},n_{33},n_{34},n_{44}.
Thomson, G. et al (1986). HLA and IDDM predisposition: new aspects. Genetic Epidemiology, 1, 262-368.
Thomson, G. (1983). Investigation of the mode of inheritance of the HLA associated diseases by the method of antigen genotype frequencies among diseased individuals. Tissue Antigens, 21, 81-104.
Wakefield, J. (2010). Bayesian methods for examining Hardy-Weinberg equilibrium. Biometrics; Vol 66:257-65
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