calculate_confidence_limit_values: Calculate the value of confidence limit

Description Usage Arguments Details Value References See Also Examples

View source: R/calculate_confidence_limit_values.R

Description

Calculates confidence limit values for prepared dataset, based on chosen parameters.

Usage

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calculate_confidence_limit_values(
  calc_dat,
  confidence_limit = 0.98,
  theoretical = FALSE,
  relative = TRUE
)

Arguments

calc_dat

processed data from DynamX file - using prepare_dataset

confidence_limit

confidence limit chosen by user - from range [0, 1].

theoretical

logical value to determine if plot is theoretical or not.

relative

logical value to determine if values are relative or absolute.

Details

...

Value

range of confidence limit interval

References

Houde, D., Berkowitz, S.A., and Engen, J.R. (2011). The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies. J Pharm Sci 100, 2071–2086.

See Also

read_hdx prepare_dataset

Examples

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# load example data
dat <- read_hdx(system.file(package = "HaDeX", "HaDeX/data/KD_180110_CD160_HVEM.csv"))

# prepare dataset for states `CD160` and `CD160_HVEM` in given time parameters 
calc_dat <- prepare_dataset(dat,
                            in_state_first = "CD160_0.001",
                            chosen_state_first = "CD160_1",
                            out_state_first = "CD160_1440",
                            in_state_second = "CD160_HVEM_0.001",
                            chosen_state_second = "CD160_HVEM_1",
                            out_state_second = "CD160_HVEM_1440")   
                            
# calculates confidence limits for prepared data  
calculate_confidence_limit_values(calc_dat = calc_dat,
                                  confidence_limit = 0.99,
                                  theoretical = FALSE, 
                                  relative = TRUE)                          
                              

HaDeX documentation built on Aug. 12, 2021, 5:20 p.m.