Contains tools for exploring Hardy-Weinberg equilibrium for diallelic genetic marker data. All classical tests (chi-square, exact, likelihood-ratio and permutation tests) for Hardy-Weinberg equilibrium are included in the package, as well as functions for power computation and for the simulation of marker data under equilibrium and disequilibrium. Routines for dealing with markers on the X-chromosome are included. Functions for testing equilibrium in the presence of missing data by using multiple imputation are also provided. Implements several graphics for exploring the equilibrium status of a large set of diallelic markers: ternary plots with acceptance regions, log-ratio plots and Q-Q plots.
|Author||Jan Graffelman <[email protected]>|
|Date of publication||2017-05-17 07:18:25 UTC|
|Maintainer||Jan Graffelman <[email protected]>|
|License||GPL (>= 2)|
|Package repository||View on CRAN|
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