Implements a methodology for the design and analysis of dose-response studies that combines aspects of multiple comparison procedures and modeling approaches (Bretz, Pinheiro and Branson, 2005, Biometrics 61, 738-748, <doi: 10.1111/j.1541-0420.2005.00344.x>). The package provides tools for the analysis of dose finding trials as well as a variety of tools necessary to plan a trial to be conducted with the MCP-Mod methodology. Please note: The 'MCPMod' package will not be further developed, all future development of the MCP-Mod methodology will be done in the 'DoseFinding' R-package.

Author | Bjoern Bornkamp, Jose Pinheiro and Frank Bretz |

Date of publication | 2016-11-24 23:33:11 |

Maintainer | Bjoern Bornkamp <bornkamp@statistik.tu-dortmund.de> |

License | GPL-3 |

Version | 1.0-9 |

**betaMod:** Beta model

**biom:** Biometrics Dose Response data

**critVal:** Calculate critical value for multiple contrast test

**emax:** Emax model

**exponential:** Exponential (power) model

**fullMod:** Calculate location and scale parameters for candidate set of...

**genDFdata:** Simulate dose-response data

**getPars:** Calculate location and scale parameters

**guesst:** Calculate guesstimates based on prior knowledge

**IBS:** Irritable Bowel Syndrome Dose Response data

**linear:** Linear Model

**linlog:** Linear in log dose Model

**logistic:** Logistic Model

**LP:** Sensitivity analysis for misspecification of standardized...

**MCPMod:** Perform MCPMod analysis of a data set

**MCPMod-internal:** Internal MCPMod functions

**MCPMod-package:** Design and Analysis of Dose-Finding Studies

**modelMeans:** Calculate mean vectors for a given candidate set

**mvtnorm.control:** Control options for pmvt and qmvt functions

**planMM:** Calculate planning quantities for MCPMod

**plot.fullMod:** Plot method for fullMod objects

**plot.LP:** Plot method for LP objects

**plot.MCPMod:** Plot MCPMod model fits

**plotModels:** Plot candidate models

**plot.planMM:** Plotting a planMM object

**plot.powerMM:** Plot method for powerMM objects

**powCalc:** Calculate the power for the multiple contrast test

**powerMM:** Calculate power for different sample sizes

**quadratic:** Quadratic model

**sampSize:** Sample size calculations for MCPMod

**sigEmax:** Sigmoid Emax Model

MCPMod

MCPMod/inst

MCPMod/inst/CITATION

MCPMod/inst/README

MCPMod/inst/doc

MCPMod/inst/doc/MCPMod.pdf

MCPMod/ToDo

MCPMod/tests

MCPMod/tests/MMTests.R

MCPMod/NAMESPACE

MCPMod/NEWS

MCPMod/data

MCPMod/data/IBS.txt.gz

MCPMod/data/biom.txt.gz

MCPMod/R

MCPMod/R/analysisMM.R
MCPMod/R/planMCPMod.R
MCPMod/MD5

MCPMod/README

MCPMod/DESCRIPTION

MCPMod/ChangeLog

MCPMod/man

MCPMod/man/critVal.Rd
MCPMod/man/biom.Rd
MCPMod/man/genDFdata.Rd
MCPMod/man/IBS.Rd
MCPMod/man/quadratic.Rd
MCPMod/man/powCalc.Rd
MCPMod/man/sampSize.Rd
MCPMod/man/modelMeans.Rd
MCPMod/man/plot.planMM.Rd
MCPMod/man/MCPMod-package.Rd
MCPMod/man/plot.powerMM.Rd
MCPMod/man/logistic.Rd
MCPMod/man/getPars.Rd
MCPMod/man/exponential.Rd
MCPMod/man/powerMM.Rd
MCPMod/man/linlog.Rd
MCPMod/man/guesst.Rd
MCPMod/man/mvtnorm.control.Rd
MCPMod/man/MCPMod-internal.Rd
MCPMod/man/sigEmax.Rd
MCPMod/man/plot.MCPMod.Rd
MCPMod/man/plot.LP.Rd
MCPMod/man/linear.Rd
MCPMod/man/betaMod.Rd
MCPMod/man/planMM.Rd
MCPMod/man/emax.Rd
MCPMod/man/plotModels.Rd
MCPMod/man/LP.Rd
MCPMod/man/plot.fullMod.Rd
MCPMod/man/fullMod.Rd
MCPMod/man/MCPMod.Rd
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