exponential: Exponential (power) model

In MCPMod: Design and Analysis of Dose-Finding Studies

Description

The model function for the exponential model is defined as

f(d,theta)=E0+E1 (exp(d/delta)-1).

Usage

exponential(dose, e0, e1, delta)

Arguments

dose	Dose variable
e0	Placebo effect
e1	E1 parameter
delta	Delta parameter, controlling the convexity of the model.

Details

This model is intended to capture a possible sub-linear or a convex dose-response relationship.

Value

Response value

References

Pinheiro, J. C., Bretz, F. and Branson, M. (2006). Analysis of dose-response studies - modeling approaches, in N. Ting (ed.). Dose Finding in Drug Development, Springer, New York, pp. 146–171

See Also

logistic, sigEmax, linlog, linear, quadratic, emax, betaMod

MCPMod documentation built on March 26, 2020, 7:28 p.m.