Matrix eQTL is designed for fast eQTL analysis on large datasets. Matrix eQTL can test for association between genotype and gene expression using linear regression with either additive or ANOVA genotype effects. The models can include covariates to account for factors as population stratification, gender, and clinical variables. It also supports models with heteroscedastic and/or correlated errors, false discovery rate estimation and separate treatment of local (cis) and distant (trans) eQTLs.
Package details 


Author  Andrey A Shabalin [aut, cre] (0000000303096821) 
Date of publication  20180113 17:07:04 UTC 
Maintainer  Andrey A Shabalin <[email protected]> 
License  LGPL3 
Version  2.2 
URL  http://www.bios.unc.edu/research/genomic_software/Matrix_eQTL/ 
Package repository  View on CRAN 
Installation 
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