In the simulated dataset 1, each subject has 1 measurement value from the new method and 10 to 15 measurement values from the reference method. Compared to the reference method, the new method has differential bias of -4 and proportional bias of 1.2. Variance of the new method is smaller than that for the reference method.
An object of class
data.frame with 1255 rows and 3 columns.
A data frame with three variables:
identification number for subjects
values from the new measurement method
values from the reference measurement method
Dataset 1 was created based on the following equations:
y_1i=-4+1.2*x_i+ε_1i, ε_1i | x_i ~ N(0,1+0.1*x_i)^2)
y_2ij=x_i+ε_2ij, ε_1i | x_i ~ N(0,(2+0.2x_i)^2)
x_i ~ Uniform[10-40]
for i = 1, 2, …, 100, j=1,2,…,n_2i and the number of repeated measurements for each subject i from the reference standard was n_2i ~ Uniform[10-15].
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