In the simulated dataset 3, each subject has 1 to 5 measurement values from the new method and 10 to 15 measurement values from the reference method. Compared to the reference method, the new method has differential bias of 3 and proportional bias of 0.9. Variance of the new method is larger than that for the reference method.
An object of class
data.frame with 1250 rows and 3 columns.
@format A data frame with three variables:
identification number for subjects
values from the new measurement method
values from the reference measurement method
Dataset 3 was created based on the following equations:
y_1ij=3+0.9*x_i+ε_1ij, ε_1ij | x_i~N(0,2+0.06*x_i)^2)
y_2ij=x_i+ε_2ij, ε_1i | x_i~N(0,(1+0.01x_i)^2)
for i = 1, 2, …, 100, j=1,2,…,n_1i or n_2i and the number of repeated measurements for each subject i from the new and reference method was n_1i ~ Uniform[1-5] and n_2i ~ Uniform[10-15] respectively.
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