In the simulated dataset 2, each subject has 1 to 5 measurement values from the new method and 10 to 15 measurement values from the reference method. Compared to the reference method, the new method has differential bias of -4 and proportional bias of 1.2. Variance of the new method is smaller than that for the reference method.
An object of class
data.frame with 1239 rows and 3 columns.
@format A data frame with three variables:
identification number for subjects
values from the new measurement method
values from the reference measurement method
Dataset 2 was created based on the following equations:
y_1ij=-4+1.2*x_i+ε_1ij, ε_1ij | x_i ~ N(0,1+0.1*x_i)^2)
y_2ij=x_i+ε_2ij, ε_1i | x_i ~ N(0,(2+0.2x_i)^2)
for i = 1, 2, …, 100, j=1,2,…,n_1i or n_2i and the number of repeated measurements for each subject i from the new and reference method was n_1i ~ Uniform[1-5] and n_2i ~ Uniform[10-15] respectively.
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