Description Usage Arguments Details Value Examples
The matchcontrolgroup function determines how well an NIPTSample fits within the NIPTControlGroup
1 2 | match_control_group(nipt_sample, nipt_control_group, mode, n_of_samples,
include_chromosomes = NULL, exclude_chromosomes = NULL)
|
nipt_sample |
The NIPTSample object that is the focus of the analysis |
nipt_control_group |
The NIPTControlGroup object used in the analysis |
mode |
The function mode. This can either be "subset" or "report". Mode "subset" means the return value will be a new 'NIPTControlGroup' object containing n samples. When mode "report" is used the output is a matrix containing the sum of squares score of the differences between the chromosomal fractions of the sample and the control for every control sample, sorted in increasing score. |
n_of_samples |
The length of the resulting NIPTControlGroup. Only applicable if mode "subset" is used. |
include_chromosomes |
integer. Include potential trisomic chromosomes into the comparison? Default = NULL, meaning chromosomes 13, 18 and 21 are not included |
exclude_chromosomes |
integer.Exclude other autosomal chromosomes besides chromosomes 13, 18 and 21? Default = NULL |
The 'matchcontrolgroup' function determines how well an NIPTSample fits within the NIPTControlGroup and, if needed, makes a subset 'NIPTControlGroup' of length n.
The output for mode subset is a new 'NIPTControlGroup' composed of _n_ samples. The output for mode report is a matrix with a single column containing the sum of squares in ascending order.
1 2 3 4 5 6 7 8 9 10 11 12 | ## Not run:
##Mode report
scores_control_group <- matchcontrolgroup(nipt_sample = sample_of_interest,
nipt_control_group = control_group,
mode = "report", include_chromosomes = c(13,18))
##Mode subset
subset_control_group <- matchcontrolgroup(nipt_sample = sample_of_interest,
nipt_control_group = control_group,
mode = "subset", n_of_samples = 50)
## End(Not run)
|
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