Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software for pharmacokinetic analysis, i.e. 'Phoenix(R) WinNonlin(R)' <https://www.certara.com/software/pkpd-modeling-and-simulation/phoenix-winnonlin/>. Some features include: 1) Use CDISC SDTM PP domain terms. 2) Automatic slope selection with the same criterion of WinNonlin(R) 3) Support both 'linear-up linear-down' and 'linear-up log-down' method 4) Calculate partial(interval) AUC with 'linear' or 'log' interpolation method For more details on noncompartmental analysis, see the reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107) *) Acknowledgement: Author thanks for the careful review and valuable input of Dr. Jee Eun Lee.

Author | Kyun-Seop Bae |

Date of publication | 2017-01-01 10:08:58 |

Maintainer | Kyun-Seop Bae <k@acr.kr> |

License | GPL-3 |

Version | 0.2.6 |

https://cran.r-project.org/package=NonCompart |

**AUC:** Calculate Area Under the Curve (AUC) and Area Under the first...

**BestSlope:** Choose best fit slope for the log(y) and x regression by the...

**IndiNCA:** Noncompartmental Analysis for an Individual

**IntAUC:** Calculate interval AUC

**Interpol:** Interpolate y value

**LinAUC:** Area Under the Curve(AUC) and Area Under the first Moment...

**LogAUC:** Area Under the Curve(AUC) and Area Under the first Moment...

**NCA:** Noncompartmental analysis for a dataset with multiple...

**NonCompart_0.2.6-package:** Noncompartmental Analysis for Pharmacokinetic Data

**Round:** Round Half Away from Zero

**RptCfg:** NCA Report Configuation Table

**Slope:** Get the Slope of regression log(y) ~ x

NonCompart

NonCompart/inst

NonCompart/inst/doc

NonCompart/inst/doc/NonCompart-manual.pdf

NonCompart/tests

NonCompart/tests/Final_Parameters_Pivoted_Theoph_Log.csv

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear.csv

NonCompart/tests/Test.R

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear_Wrong_Extravascular.csv

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Log_Wrong_Extravascular.csv

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Log_Infusion.csv

NonCompart/tests/Final_Parameters_Pivoted_Theoph_Linear.csv

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Log.csv

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear_Infusion.csv

NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear_NoDose.csv

NonCompart/NAMESPACE

NonCompart/R

NonCompart/R/IntAUC.R
NonCompart/R/LinAUC.R
NonCompart/R/BestSlope.R
NonCompart/R/Round.R
NonCompart/R/AUC.R
NonCompart/R/sysdata.rda

NonCompart/R/Interpol.R
NonCompart/R/NCA.R
NonCompart/R/LogAUC.R
NonCompart/R/IndiNCA.R
NonCompart/R/Slope.R
NonCompart/MD5

NonCompart/DESCRIPTION

NonCompart/man

NonCompart/man/RptCfg.Rd
NonCompart/man/Interpol.Rd
NonCompart/man/IndiNCA.Rd
NonCompart/man/AUC.Rd
NonCompart/man/NonCompart_0.2.6-package.Rd
NonCompart/man/BestSlope.Rd
NonCompart/man/LogAUC.Rd
NonCompart/man/LinAUC.Rd
NonCompart/man/NCA.Rd
NonCompart/man/IntAUC.Rd
NonCompart/man/Slope.Rd
NonCompart/man/Round.Rd
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