Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software for pharmacokinetic analysis, i.e. 'Phoenix(R) WinNonlin(R)' <https://www.certara.com/software/pkpd-modeling-and-simulation/phoenix-winnonlin/>. Some features include: 1) Use CDISC SDTM PP domain terms. 2) Automatic slope selection with the same criterion of WinNonlin(R) 3) Support both 'linear-up linear-down' and 'linear-up log-down' method 4) Calculate partial(interval) AUC with 'linear' or 'log' interpolation method For more details on noncompartmental analysis, see the reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107) *) Acknowledgement: Author thanks for the careful review and valuable input of Dr. Jee Eun Lee.
|Date of publication||2017-01-01 10:08:58|
|Maintainer||Kyun-Seop Bae <email@example.com>|
AUC: Calculate Area Under the Curve (AUC) and Area Under the first...
BestSlope: Choose best fit slope for the log(y) and x regression by the...
IndiNCA: Noncompartmental Analysis for an Individual
IntAUC: Calculate interval AUC
Interpol: Interpolate y value
LinAUC: Area Under the Curve(AUC) and Area Under the first Moment...
LogAUC: Area Under the Curve(AUC) and Area Under the first Moment...
NCA: Noncompartmental analysis for a dataset with multiple...
NonCompart_0.2.6-package: Noncompartmental Analysis for Pharmacokinetic Data
Round: Round Half Away from Zero
RptCfg: NCA Report Configuation Table
Slope: Get the Slope of regression log(y) ~ x