NonCompart: Noncompartmental Analysis for Pharmacokinetic Data

Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software for pharmacokinetic analysis, i.e. 'Phoenix(R) WinNonlin(R)' <https://www.certara.com/software/pkpd-modeling-and-simulation/phoenix-winnonlin/>. Some features include: 1) Use CDISC SDTM PP domain terms. 2) Automatic slope selection with the same criterion of WinNonlin(R) 3) Support both 'linear-up linear-down' and 'linear-up log-down' method 4) Calculate partial(interval) AUC with 'linear' or 'log' interpolation method For more details on noncompartmental analysis, see the reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107) *) Acknowledgement: Author thanks for the careful review and valuable input of Dr. Jee Eun Lee.

AuthorKyun-Seop Bae
Date of publication2017-01-01 10:08:58
MaintainerKyun-Seop Bae <k@acr.kr>
LicenseGPL-3
Version0.2.6
https://cran.r-project.org/package=NonCompart

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Files

NonCompart
NonCompart/inst
NonCompart/inst/doc
NonCompart/inst/doc/NonCompart-manual.pdf
NonCompart/tests
NonCompart/tests/Final_Parameters_Pivoted_Theoph_Log.csv
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear.csv
NonCompart/tests/Test.R
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear_Wrong_Extravascular.csv
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Log_Wrong_Extravascular.csv
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Log_Infusion.csv
NonCompart/tests/Final_Parameters_Pivoted_Theoph_Linear.csv
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Log.csv
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear_Infusion.csv
NonCompart/tests/Final_Parameters_Pivoted_Indometh_Linear_NoDose.csv
NonCompart/NAMESPACE
NonCompart/R
NonCompart/R/IntAUC.R NonCompart/R/LinAUC.R NonCompart/R/BestSlope.R NonCompart/R/Round.R NonCompart/R/AUC.R
NonCompart/R/sysdata.rda
NonCompart/R/Interpol.R NonCompart/R/NCA.R NonCompart/R/LogAUC.R NonCompart/R/IndiNCA.R NonCompart/R/Slope.R
NonCompart/MD5
NonCompart/DESCRIPTION
NonCompart/man
NonCompart/man/RptCfg.Rd NonCompart/man/Interpol.Rd NonCompart/man/IndiNCA.Rd NonCompart/man/AUC.Rd NonCompart/man/NonCompart_0.2.6-package.Rd NonCompart/man/BestSlope.Rd NonCompart/man/LogAUC.Rd NonCompart/man/LinAUC.Rd NonCompart/man/NCA.Rd NonCompart/man/IntAUC.Rd NonCompart/man/Slope.Rd NonCompart/man/Round.Rd

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