gIntAUC: Calculate interval AUC of general form

In NonCompart: Noncompartmental Analysis for Pharmacokinetic Data

Calculate interval AUC of general form

Description

It calculates interval AUC of general form. This is useful for pharmacodynamic data.

Usage

gIntAUC(x, y, t1, t2, Outer = "NEAREST")

Arguments

x	vector values of independent variable, usually time
y	vector values of dependent variable, usually concentration
t1	start time for AUC
t2	end time for AUC
Outer	indicates how to do the out of x range point

Details

This calculates an interval (partial) AUC (from t1 to t2) with the given series of x and y. If t1 and/or t2 cannot be found within x vector, it interpolates. If t1 and/or t2 are out of x range, it uses the nearest value. For concentration data, use IntAUC.

Value

return interval AUC value (scalar)

Author(s)

Kyun-Seop Bae <[e-mail]>

See Also

gAUC, gInterpol, tblAUC

Examples

gIntAUC(Theoph[Theoph$Subject==1, "Time"], Theoph[Theoph$Subject==1, "conc"], t1=0.5, t2=11)

NonCompart documentation built on Nov. 15, 2023, 9:06 a.m.