DetSlope: Determine slope for the log(y) and x regression manually

In NonCompart: Noncompartmental Analysis for Pharmacokinetic Data

Determine slope for the log(y) and x regression manually

Description

You choose a slope for terminal half-life.

Usage

DetSlope(x, y, SubTitle="", sel.1=0, sel.2=0)

Arguments

x	vector values of x-axis, usually time
y	vector values of y-axis, usually concentration
SubTitle	subtitle to be shown on the plot
sel.1	default index of the first element to use
sel.2	default index of the last element to use

Details

Sometimes BestSlope cannot find terminal slope satisfactorily. Then you can use this function to choose manually. It returns the same format result with BestSlope with an attribute indicating used points.

Value

R2	R-squared
R2ADJ	adjusted R-squared
LAMZNPT	number of points used for the slope
LAMZ	negative of the slope, lambda_z
b0	intercept of the regression line
CORRXY	correlation of log(y) and x
LAMZLL	earliest x for lambda_z
LAMZUL	last x for lambda_z
CLSTP	predicted y value at the last point, predicted concentration for the last time point

Author(s)

Kyun-Seop Bae <[e-mail]>

See Also

Slope

Examples

DetSlope(Theoph[Theoph$Subject==1, "Time"], Theoph[Theoph$Subject==1, "conc"])
DetSlope(Indometh[Indometh$Subject==2, "time"], Indometh[Indometh$Subject==2, "conc"])

NonCompart documentation built on Nov. 15, 2023, 9:06 a.m.