OneArmPhaseTwoStudy: Planing, Monitoring and Evaluating Oncological Phase 2 Studies
Version 0.1.6

Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are single-arm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate 'Simon's two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with this package a good starting point is to take a closer look at the functions getSolutions() and getSolutionsSub1().The web-based tool (https://imbi.shinyapps.io/phaseII-app/) extends the functionality of our R package by means of a proper dealing with over- and underrunning. The R function binom.test of the 'stats' R package and the package 'binom' might be helpful to assess the performance of the corresponding one-stage design as a reference.

Getting started

Package details

AuthorMarius Wirths
Date of publication2016-05-23 11:28:04
MaintainerMarius Wirths <wirths@imbi.uni-heidelberg.de>
LicenseGPL (>= 2)
Version0.1.6
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("OneArmPhaseTwoStudy")

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OneArmPhaseTwoStudy documentation built on May 29, 2017, 7:02 p.m.