Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are singlearm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate 'Simon's twostage designs' and 'socalled' 'subset designs'. If you are unfamiliar with this package a good starting point is to take a closer look at the functions getSolutions() and getSolutionsSub1().The webbased tool (<https://imbi.shinyapps.io/phaseIIapp/>) extends the functionality of our R package by means of a proper dealing with over and underrunning. The R function binom.test of the 'stats' R package and the package 'binom' might be helpful to assess the performance of the corresponding onestage design as a reference.
Package details 


Author  Marius Wirths 
Maintainer  Johannes Krisam <krisam@imbi.uniheidelberg.de> 
License  GPL (>= 2) 
Version  1.0.3 
Package repository  View on CRAN 
Installation 
Install the latest version of this package by entering the following in R:

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