get_conditionalPower: Calculates the conditional power.

In OneArmPhaseTwoStudy: Planning, Conducting, and Analysing Single-Arm Phase II Studies

Description

Calculates the conditional power of a given subset design.

Usage

get_conditionalPower(t, u, enrolled, r1, n1, r, s, n, pc1, pt1,
  sub1 = setupSub1Design())

Arguments

t	observed responses in the subset endpoint.
u	observed responses in the superset endpoint.
enrolled	number of patients enrolled so far.
r1	critical value for the first stage.
n1	sample size for the first stage.
r	critical value for the subset endpoint.
s	critical value for the superset endpoint.
n	overall sample size.
pc1	the response probability under the alternative hypothesis for the subset endpoint.
pt1	the response probability under the alternative hypothesis for the superset endpoint.
sub1	"sub1"-object used to calculate the p value in c++ .

See Also

setupSub1Design

Examples

#Setup "sub1"-object
sub1 <- setupSub1Design(pc0 = 0.5, pt0 = 0.6)

#Calculate a  subset design
design <- getSolutionsSub1(sub1, skipN1 = FALSE)$Solutions[4,]

t <- 5
u <- 7
enrolled <- 10

con_p <- get_conditionalPower(t, u, enrolled, design$r1,
design$n1, design$r, design$s, design$n, design$pc1, design$pt1, sub1)

OneArmPhaseTwoStudy documentation built on May 2, 2019, 9:28 a.m.