Calculates the conditional error for all possible outcomes at the interim analysis (different number of responses) spending "rest alpha" (difference between nominal alpha level and actual alpha level) proportionally.
a dataframe containing all critical values for a Simon's two-stage design defined by the colums "r1", "n1", "r", "n" and "p0".
overall significance level the trial was planned for.
Englert S., Kieser M. (2012): Adaptive designs for single-arm phase II trials in oncology. Pharmaceutical Statistics 11,241-249.
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