Description Usage Arguments Value References Examples
A vector of the computed Bayes factors for the tested pathways.
1 | NBF(y, G, P, a, b, s2, nu)
|
y |
Response vector of length N |
G |
Genotype matrix, with N rows and L columns (number of tested SNPs) |
P |
Pathway matrix, with L columns and M columns (number of tested pathways) |
a |
Hyper-parameter of the variance assumed for the integrated out SNP effects |
b |
Hyper-parameter of the variance assumed for the pathway effects |
s2 |
Hyper-parameter of the Inverse-Chi-squared distribution assumed for the variance of the response vector |
nu |
Hyper-parameter of the Inverse-Chi-squared distribution assumed for the variance of the response vector |
A vector of the computed Bayes factors of the same length as the number of tested pathways
Evangelou, M., Dudbridge, F., Wernisch, L. (2014). Two novel pathway analysis methods based on a hierarchical model. Bioinformatics, 30(5), 690 - 697.
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